Download PDF by F. Lang, M. Ritter, H. Völkl, D. Häussinger (auth.), Prof.: Advances in Comparative and Environmental Physiology:

By F. Lang, M. Ritter, H. Völkl, D. Häussinger (auth.), Prof. Dr. Florian Lang, Prof. Dr. Dieter Häussinger (eds.)

ISBN-10: 3642771246

ISBN-13: 9783642771248

ISBN-10: 3642771262

ISBN-13: 9783642771262

One of the necessities for survival is the power of cells to take care of their quantity. hence, in the course of the process evolution cells have "learned" various ideas to accomplish quantity homeostasis. This quantity regulatory equipment includes law of either, mobile metabolism and mobile delivery and is exploited via hormones and transmitters to manage cellularfunction. This publication to illustrates the complicated interaction of phone quantity regulatory mechanisms and mobile functionality in various tissues. besides the fact that, our wisdom continues to be faraway from being conclusive, and the current choice of stories is assumed to foster extra experimental efforts to solve the function of phone quantity within the built-in functionality of cells.

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Extra resources for Advances in Comparative and Environmental Physiology: Interaction of Cell Volume and Cell Function

Example text

1, addition of glutamine to isolated perfused rat liver creates within about 12 min an intra/extracellular glutamine concentration gradient of about 12. During the first 2 min of glutamine accumulation, liver mass increases rapidly due to cell swelling, as validated by measurements of intracellular water space (vom Dahl et al. 1991d). Hepatic net K+ uptake during this phase is probably due to extrusion of Na+ by Na+/K+ ATPase. Thereafter, no further increase in liver mass is observed, despite continuing accumulation of glutamine inside the cell.

1991a,c). Remarkably, halfmaximal insulin-induced cell swelling and half-maximal glucagon-induced cell shrinkage in perfused rat liver are found at hormone concentrations normally present in portal venous blood in vivo (vom Dahl et al. 1991c; Fig. 3). Accordingly, one is tempted to speculate that physiological fluctuations of the portal insulin and glucagon concentrations may modify liver cell volume also in vivo. In perfused rat liver, vasopressin exhibits only minor effects on cell volume, but shrinks the cells when added on top of glucagon or cAMP (vom Dahl et al.

J Membr Bioi 82: 95-104 Kramhoft B, Lambert IH, Hoffmann EK, Jorgensen F (1986) Activation of CI-dependent K transport in Ehrlich ascites tumor cells. Am J Physiol 251: C369-C379 Kregenow FM (1971) The response of duck erythrocytes to nonhemolytic hypotonic media. Evidence for a volume-controlling mechanism. J Gen Physiol 58: 372-395 Kregenow FM (1981) Osmoregulatory salt transporting mechanisms: control of cell volume in anisotonic media. Annu Rev Physiol 43: 493-505 Kregenow FM, Caryk T, Siebens AW (1985) Further studies of the volume-regulatory response of Amphiuma red cells in hypertonic media.

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Advances in Comparative and Environmental Physiology: Interaction of Cell Volume and Cell Function by F. Lang, M. Ritter, H. Völkl, D. Häussinger (auth.), Prof. Dr. Florian Lang, Prof. Dr. Dieter Häussinger (eds.)


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